Have a party!
Or, more accurately, have a Seudah, a meal, which should have bread at its center. Many also try to fulfill the Talmudic claim, ‘to be so drunk as to not know the difference between Mordechai and Haman.’ There are a lot of different interpretations of this line! So if drinking is good for you, zay gezunt! But if not, there are ways to celebrate without wine!